In this issue, first, Quaghebeur et al. [1] discusses the biomechanics of the pelvic floor in order to emphasize the role of muscles and ligaments in maintaining continence and pelvic organ function. Wright et al. [2] studied on periurethral botulinum toxin injections for women with chronic urinary retention and they demonstrated the long-term safety and efficacy of this treatment. Meanwhile, Kingsley et al. [3] reviewed that alpha-1 adrenergic receptor antagonists and found limited evidence of their impact on cognitive function and confirmed their safety in treating benign prostatic hyperplasia. In addition, Bellucci et al. [4] demonstrated that the PIEZO2 gene is linked to bladder dysfunction in bladder outlet obstruction patients, suggesting it as a potential therapeutic target. Further, a study on neurogenic detrusor overactivity identifies urinary incontinence episodes and involuntary bladder contractions as predictors of resistance to anticholinergic treatment [5].

This issue also introduces various tool and techniques on lifecycle support with urinary disorders. In the study, Kuroda et al. [6] applied the International Consultation on Incontinence Questionnaire Short Form questionnaire as a useful alternative to the 1-hour pad test for evaluating urinary incontinence in patients undergoing pelvic organ prolapse surgery. Also, Kang et al. [7] revealed that the use of holmium laser in prostate surgery shows how the distance between the laser tip and tissue affects the degree of tissue destruction. This offers insights for optimizing surgical techniques. For a new innovation or therapeutic techniques, Park et al. [8] explored serious games as promising tools for managing pediatric urological conditions, such as bedwetting, by providing long-term symptom management. For the public perceptions of enuresis, Yu et al. [9] revealed differences between South Korea and the United States online communities, with Koreans more likely to rely on nonprofessional opinions.

As we move forward, these studies exemplify the dynamic nature of urological research. By pushing the boundaries of knowledge, exploring novel therapies, and refining diagnostic tools, the field continues to offer hope for improved patient outcomes and quality of life. We encourage readers to engage with these articles and consider the broader implications of these advancements in their own practice and research.