On the Site and Mechanism of Action of β₃-Adrenoceptor Agonists in the Bladder

  

Pathophysiology of Overactive Bladder and Pharmacologic Treatments Including β3-Adrenoceptor Agonists -Basic Research Perspectives-

Joonbeom Kwon, Duk Yoon Kim, Kang Jun Cho, Mamoru Hashimoto, Kanako Matsuoka, Tadanobu Kamijo, Zhou Wang, Sergei Karnup, Anne M. Robertson, Pradeep Tyagi, Naoki Yoshimura

International Neurourology Journal.2024; 28(Suppl 1): 12.     CrossRef

The large part German medicine has played in the development of experimental pharmacology in Japan

Yuichi Hattori, Kuniaki Ishii, Kazuhiko Yanai, Masao Endoh

Naunyn-Schmiedeberg's Archives of Pharmacology.2023; 396(1): 35.     CrossRef

Effect of β3‐adrenoceptor agonist on the micromotion of bilateral major pelvic ganglion‐excised rat bladder

Hee Seo Son, Soo Young Moon, Joonbeom Kwon, Jang Hwan Kim

Neurourology and Urodynamics.2023; 42(2): 530.     CrossRef

Vibegron shows high efficacy in pediatric patients with refractory daytime urinary incontinence

Taiju Hyuga, Kazuya Tanabe, Taro Kubo, Shigeru Nakamura, Hideo Nakai, Kimihiko Moriya

Neurourology and Urodynamics.2023; 42(4): 794.     CrossRef

Inhibition of prejunctional parasympathetic pathways by β3-adrenoceptor agonists in the isolated pig detrusor: comparison with human detrusor studies

Gianluigi D’Agostino, Stefano Salvatore, Paolo Calvi, Anna Maria Condino

Frontiers in Pharmacology.2023;[Epub]     CrossRef

Mirabegron is better tolerated than solifenacin in Sjogren's syndrome patients with overactive bladder symptoms—A randomized controlled trial

Hao Xiang Chen, Shih‐Hsin Chang, Der‐Yuan Chen, Joung‐Liang Lan, Kai‐Jieh Yeo, Po‐Hao Huang, Chung‐Ming Huang, Chi‐Ping Huang, Eric Chieh‐Lung Chou, Po‐Chang Wu

LUTS: Lower Urinary Tract Symptoms.2023; 15(4): 139.     CrossRef

Update on Overactive Bladder Therapeutic Options

Caroline P. Babin, Nicole T. Catalano, David M. Yancey, Nathan Z. Pearl, Eleanor M. Koonce, Shahab Ahmadzadeh, Sahar Shekoohi, Elyse M. Cornett, Alan D. Kaye

American Journal of Therapeutics.2023;[Epub]     CrossRef

Management of use of urinary antimuscarinics and alpha blockers for benign prostatic hyperplasia in older adults at risk of falls: a clinical review

Birkan İlhan, Tuğba Erdoğan, Eva Topinková, Gülistan Bahat

European Geriatric Medicine.2023; 14(4): 733.     CrossRef

Treating LUTS in Men with Benign Prostatic Obstruction: A Review Article

Liam Murad, David Bouhadana, David-Dan Nguyen, Bilal Chughtai, Kevin C. Zorn, Naeem Bhojani, Dean S. Elterman

Drugs & Aging.2023; 40(9): 815.     CrossRef

Comparison of add-on medications for persistent storage symptoms after α-blocker treatment in BPH patients – a network meta-analysis

Yi-Ting Su, Hsiao-Ling Chen, Jeremy Yuen-Chun Teoh, Vinson Wai-Shun Chan, Wen-Jeng Wu, Hsiang-Ying Lee

BMC Urology.2023;[Epub]     CrossRef

Zirconium Oxide Nanostructure Integrated Screen-Printed Mirabegron Voltammetric Sensors

Razan M. Snari, Arwa Alharbi, Alaa M. Munshi, Zehbah A. Al-Ahmed, Enas Aljuhani, Ahmad A. Alluhaybi, Ismail Althagafi, Nashwa M. El-Metwaly

Journal of The Electrochemical Society.2023; 170(11): 113506.     CrossRef

Clinical Report of Baliao Electroacupuncture Treatment on a Stroke Patient Suffering from a Neurogenic Overactive Bladder

Ye-Chae Hwang, Hye-Jin Lee, Hye-Min Heo, Gyu-Ri Jeon, Seung-Yeon Cho, Seong-Uk Park, Chang-Nam Ko, Jung-Mi Park

The Journal of Internal Korean Medicine.2022; 43(1): 90.     CrossRef

Continuous administration of mirabegron has advantages in inhibition of central sensitization compared with short‐term treatment cessation in a mouse model of overactive bladder

Joonbeom Kwon, Eun‐Ju Lee, Hye‐Ri Park, Hyun‐Jung Cho, Ji‐Ae Jang, Hyoungoh Yang, Jihyun An, Donghwi Park, Yeon‐Joo Kim, Kyung‐Jae Hur, Jae‐Soo Kim, Naoki Yoshimura

Neurourology and Urodynamics.2022; 41(6): 1355.     CrossRef

Mirabegron and solifenacin are effective for the management of the increased urinary frequency induced by psychological stress in female mice

Eliza G. West, Catherine McDermott, Russ Chess-Williams, Donna J. Sellers

Scientific Reports.2022;[Epub]     CrossRef

β3 Relaxant Effect in Human Bladder Involves Cystathionine γ-Lyase-Derived Urothelial Hydrogen Sulfide

Emma Mitidieri, Annalisa Pecoraro, Erika Esposito, Vincenzo Brancaleone, Carlotta Turnaturi, Luigi Napolitano, Vincenzo Mirone, Ferdinando Fusco, Giuseppe Cirino, Raffaella Sorrentino, Giulia Russo, Annapina Russo, Roberta d’Emmanuele di Villa Bianca

Antioxidants.2022; 11(8): 1480.     CrossRef

Novel botulinum neurotoxin-A tibial nerve perineural injection to alleviate overactive bladder symptoms in male rats

Seungbeom Kim, Hyun Seok Na, Jong Mok Park, Jin Wook Kim

Animal Cells and Systems.2022; 26(6): 283.     CrossRef

Fluoxetine, a selective serotonin reuptake inhibitor used clinically, improves bladder function in a mouse model of moderate spinal cord injury

Long Ma, Jing-Yuan Tang, Jin-Yong Zhou, Chen Zhu, Xin Zhang, Ping Zhou, Qiu Yu, Yan Wang, Xiao-Jian Gu

Neural Regeneration Research.2021; 16(10): 2093.     CrossRef

Hyperactive bladder: concept of disease and paradigms in the treatment

G. G. Krivoborodov, E. I. Tur, D. A. Shirin

Meditsinskiy sovet = Medical Council.2021; (4): 121.     CrossRef

Mirabegron has longer treatment persistence than antimuscarinics: Real‐world data from a Korean national cohort database

Kyu‐Sung Lee, Hyejeong Park, Danbee Kang, Hye J. Byun, Chee Y. Foo, Farid A. Hadi, Soyoung Kim, Juhee Cho

Neurourology and Urodynamics.2021; 40(8): 1972.     CrossRef

Irreversible effects of anticholinergic withdrawal in the elderly: a case report

Charisse Chehovich

Aging Pathobiology and Therapeutics.2021; 3(2): 28.     CrossRef

The actual pharmacotherapy benign hyperplasia according to EAU Guidelines

Aleš Horák

Urologie pro praxi.2021; 22(3): 125.     CrossRef

Contractile elements and their sympathetic regulations in the pig urinary bladder: a species and regional comparative study

Retsu Mitsui, Ken Lee, Aoi Uchiyama, Shunta Hayakawa, Fumio Kinoshita, Shunichi Kajioka, Masatoshi Eto, Hikaru Hashitani

Cell and Tissue Research.2020; 379(2): 373.     CrossRef

Cardiovascular safety of antimuscarinic add‐on therapy in patients with overactive bladder who had a suboptimal response to mirabegron monotherapy: A post hoc analysis from the Japanese MILAI II study

Takao Katoh, Yasuhiko Igawa, Osamu Yamaguchi, Daisuke Kato, Takuya Hamada, Kentaro Kuroishi

LUTS: Lower Urinary Tract Symptoms.2020; 12(1): 68.     CrossRef

Pharmacological properties of β-adrenoceptors mediating rat superior mesenteric artery relaxation and the effects of chemical sympathetic denervation

Keisuke Obara, Mai Shigematsu, Hiromi Takahasi, Yuri Iiboshi, Kento Yoshioka, Yoshitoshi Kasuya, Yoshio Tanaka

Life Sciences.2020; 241: 117155.     CrossRef

β3 Adrenoceptor‐induced cholinergic inhibition in human and rat urinary bladders involves the exchange protein directly activated by cyclic AMP 1 favoring adenosine release

Isabel Silva, M. Teresa Magalhães‐Cardoso, Fátima Ferreirinha, Sílvia Moreira, Ana Filipa Costa, Diogo Silva, Cátia Vieira, Miguel Silva‐Ramos, Paulo Correia‐de‐Sá

British Journal of Pharmacology.2020; 177(7): 1589.     CrossRef

Validated spectrofluorimetric method for determination of mirabegron by utilizing its quenching effect on acetoxymercuric fluorescein reagent

S. Morshedy, G. Omran, O.A. Abdullatef, M. Omar, W. Talaat

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy.2020; 239: 118509.     CrossRef

Potential of Mirabegron and its Extended-release Formulations for the Treatment of Overactive Bladder Syndrome

Pankaj Mandpe, Bala Prabhakar, Pravin Shende

Current Drug Metabolism.2020; 21(2): 79.     CrossRef

Future Directions for Neurourological Research

Young Sam Cho

International Neurourology Journal.2020; 24(3): 189.     CrossRef

Design, synthesis and in vitro evaluation of a Dopa-organoboron compound that acts as a bladder relaxant through non-catecholamine receptors

Ana L. Ocampo-Néstor, Ruth M. López-Mayorga, Enrique F. Castillo-Henkel, Itzia I. Padilla-Martínez, José G. Trujillo-Ferrara, Marvin A. Soriano-Ursúa

Molecular Diversity.2019; 23(2): 361.     CrossRef

Mirabegron induces relaxant effects via cAMP signaling‐dependent and ‐independent pathways in detrusor smooth muscle

Tomoko Maki, Shunichi Kajioka, Momoe Itsumi, Eljamal Kareman, Ken Lee, Masaki Shiota, Masatoshi Eto

LUTS: Lower Urinary Tract Symptoms.2019;[Epub]     CrossRef

β3-Adrenoceptor agonists inhibit purinergic receptor-mediated contractions of the murine detrusor

Zhihui Fong, Caoimhín S. Griffin, Mark A. Hollywood, Keith D. Thornbury, Gerard P. Sergeant

American Journal of Physiology-Cell Physiology.2019; 317(1): C131.     CrossRef

Updating the evidence on drugs to treat overactive bladder: a systematic review

Frances C. Hsu, Chandler E. Weeks, Shelley S. Selph, Ian Blazina, Rebecca S. Holmes, Marian S. McDonagh

International Urogynecology Journal.2019; 30(10): 1603.     CrossRef

Anti-cholinergic medications for bladder dysfunction worsen cognition in persons with multiple sclerosis

Sarah A. Morrow, Heather Rosehart, Alp Sener, Blayne Welk

Journal of the Neurological Sciences.2018; 385: 39.     CrossRef

Mirabegron: potential off target effects and uses beyond the bladder

Nodi Dehvari, Edilson Dantas da Silva Junior, Tore Bengtsson, Dana Sabine Hutchinson

British Journal of Pharmacology.2018; 175(21): 4072.     CrossRef

β3‐adrenoceptor agonists inhibit carbachol‐evoked Ca2+ oscillations in murine detrusor myocytes

Caoimhin S. Griffin, Eamonn Bradley, Mark A. Hollywood, Noel G. McHale, Keith D. Thornbury, Gerard P. Sergeant

BJU International.2018; 121(6): 959.     CrossRef

Contribution of pharmacological research to the discovery of a first-in-class drug, mirabegron, for the treatment of overactive bladder

Koji Ueshima, Masashi Ukai

Folia Pharmacologica Japonica.2018; 152(3): 111.     CrossRef

Broaden and Build Up Knowledge Based on Investigative and Clinical Research

Khae Hawn Kim

International Neurourology Journal.2017; 21(1): 3.     CrossRef

A Clinician’s Perspective on the Mechanism of β3-Adrenoceptor Agonists in the Bladder

Tack Lee

International Neurourology Journal.2017; 21(1): 1.     CrossRef

Re: Inhibition of Cholinergic Neurotransmission by β 3 -adrenoceptors Depends on Adenosine Release and A 1 Receptors Activation in Human and Rat Urinary Bladders

Karl-Erik Andersson

European Urology.2017; 72(4): 650.     CrossRef

The Influence of Resiniferatoxin (RTX) and Tetrodotoxin (TTX) on the Distribution, Relative Frequency, and Chemical Coding of Noradrenergic and Cholinergic Nerve Fibers Supplying the Porcine Urinary Bladder Wall

Ewa Lepiarczyk, Agnieszka Bossowska, Jerzy Kaleczyc, Agnieszka Skowrońska, Marta Majewska, Michal Majewski, Mariusz Majewski

Toxins.2017; 9(10): 310.     CrossRef