Function of the Cold Receptor (TRPM8) Associated with Voiding Dysfunction in Bladder Outlet Obstruction in Rats

  

Efficacy of KPR‐5714, a selective transient receptor potential melastatin 8 antagonist, on chronic psychological stress‐induced bladder overactivity in male rats

Shinjiro Watanabe, Shingo Miyazaki, Yu Yumoto, Jun‐ichi Kobayashi, Yoshikazu Fujimori

Neurourology and Urodynamics.2023; 42(8): 1812.     CrossRef

The TRPM8 channel as a potential therapeutic target for bladder hypersensitive disorders

Naoki Aizawa, Tomoe Fujita

Journal of Smooth Muscle Research.2022; 58: 11.     CrossRef

Transient receptor potential channels in sensory mechanisms of the lower urinary tract

Matthias Vanneste, Andrei Segal, Thomas Voets, Wouter Everaerts

Nature Reviews Urology.2021; 18(3): 139.     CrossRef

UCP1 and TRPM8 Expression in the Brown Fat Did Not Affect the Restriction of Menthol-Induced Hyperthermia by Estradiol in Ovariectomized Rats

Yuki UCHIDA, Izumi SATO, Koyuki ATSUMI, Chinami TSUNEKAWA

Journal of Nutritional Science and Vitaminology.2021; 67(2): 130.     CrossRef

Current Knowledge on the Vascular Effects of Menthol

Henrique Silva

Frontiers in Physiology.2020;[Epub]     CrossRef

TRPM8 channels: A review of distribution and clinical role

Yuqian Liu, Reyaj Mikrani, Yanjun He, Mirza Muhammad Faran Ashraf Baig, Muhammad Abbas, Muhammad Naveed, Meng Tang, Qin Zhang, Cuican Li, Xiaohui Zhou

European Journal of Pharmacology.2020; 882: 173312.     CrossRef

The Urothelium: Life in a Liquid Environment

Marianela G. Dalghi, Nicolas Montalbetti, Marcelo D. Carattino, Gerard Apodaca

Physiological Reviews.2020; 100(4): 1621.     CrossRef

Changes in the expression and function of the PDE5 pathway in the obstructed urinary bladder

Weixiang He, Han Xiang, Daoquan Liu, Jianmin Liu, Mingzhou Li, Qian Wang, Qiaofeng Qian, Yan Li, Xun Fu, Ping Chen, Yuming Guo, Guang Zeng, Zhonghua Wu, Daxing Zhan, Xinghuan Wang, Michael E. DiSanto, Xinhua Zhang

Journal of Cellular and Molecular Medicine.2020; 24(22): 13181.     CrossRef

RQ-00434739, a novel TRPM8 antagonist, inhibits prostaglandin E2-induced hyperactivity of the primary bladder afferent nerves in rats

Naoki Aizawa, Hiroyuki Ohshiro, Shuzo Watanabe, Haruki Kume, Yukio Homma, Yasuhiko Igawa

Life Sciences.2019; 218: 89.     CrossRef

Benefits and limitations of animal models in partial bladder outlet obstruction for translational research

Takeya Kitta, Yukiko Kanno, Hiroki Chiba, Madoka Higuchi, Mifuka Ouchi, Mio Togo, Kimihiko Moriya, Nobuo Shinohara

International Journal of Urology.2018; 25(1): 36.     CrossRef

KPR‐2579, a novel TRPM8 antagonist, inhibits acetic acid‐induced bladder afferent hyperactivity in rats

Naoki Aizawa, Yoshikazu Fujimori, Jun‐ichi Kobayashi, Osamu Nakanishi, Hideaki Hirasawa, Haruki Kume, Yukio Homma, Yasuhiko Igawa

Neurourology and Urodynamics.2018; 37(5): 1633.     CrossRef

Novel selective, potent naphthyl TRPM8 antagonists identified through a combined ligand- and structure-based virtual screening approach

Andrea R. Beccari, Marica Gemei, Matteo Lo Monte, Nazareno Menegatti, Marco Fanton, Alessandro Pedretti, Silvia Bovolenta, Cinzia Nucci, Angela Molteni, Andrea Rossignoli, Laura Brandolini, Alessandro Taddei, Lorena Za, Chiara Liberati, Giulio Vistoli

Scientific Reports.2017;[Epub]     CrossRef

Functional role of the transient receptor potential melastatin 8 (TRPM8) ion channel in the urinary bladder assessed by conscious cystometry and ex vivo measurements of single‐unit mechanosensitive bladder afferent activities in the rat

Hiroki Ito, Naoki Aizawa, Rino Sugiyama, Shuzo Watanabe, Nobuyuki Takahashi, Masaomi Tajimi, Hiroshi Fukuhara, Yukio Homma, Yoshinobu Kubota, Karl‐Erik Andersson, Yasuhiko Igawa

BJU International.2016; 117(3): 484.     CrossRef

On the origin of spontaneous activity in the bladder

Nobuhiro Kushida, Christopher H. Fry

BJU International.2016; 117(6): 982.     CrossRef

TRPM8: a potential target for cancer treatment

Zhaoguo Liu, Hongyan Wu, Zhonghong Wei, Xu Wang, Peiliang Shen, Siliang Wang, Aiyun Wang, Wenxing Chen, Yin Lu

Journal of Cancer Research and Clinical Oncology.2016; 142(9): 1871.     CrossRef

TRP channels in lower urinary tract dysfunction

J Franken, P Uvin, D De Ridder, T Voets

British Journal of Pharmacology.2014; 171(10): 2537.     CrossRef

The Region Adjacent to the C-end of the Inner Gate in Transient Receptor Potential Melastatin 8 (TRPM8) Channels Plays a Central Role in Allosteric Channel Activation

Francisco José Taberner, Ainara López-Córdoba, Gregorio Fernández-Ballester, Yuri Korchev, Antonio Ferrer-Montiel

Journal of Biological Chemistry.2014; 289(41): 28579.     CrossRef

Caffeine enhances micturition through neuronal activation in micturition centers

YOUNG-SAM CHO, IL-GYU KO, SUNG-EUN KIM, LAKKYONG HWAN, MAL-SOON SHIN, CHANG-JU KIM, SANG-HOON KIM, JUN-JANG JIN, JUN-YOUNG CHUNG, KHAE-HAWN KIM

Molecular Medicine Reports.2014; 10(6): 2931.     CrossRef

Menthol relaxes rat aortae, mesenteric and coronary arteries by inhibiting calcium influx

Wai San Cheang, Muk Yan Lam, Wing Tak Wong, Xiao Yu Tian, Chi Wai Lau, Zhiming Zhu, Xiaoqiang Yao, Yu Huang

European Journal of Pharmacology.2013; 702(1-3): 79.     CrossRef